What is a major cause of dysplasia?

Dysplasia refers to the abnormal development or growth of tissues or cells within a specific organ or area of the body. Chronic irritation or inflammation is a predominant cause of dysplasia because it leads to repeated cycles of cellular injury and repair, prompting the cells to undergo changes in their structure and function.

This persistent irritation can arise from factors such as ongoing inflammation due to infections, exposure to toxins, or persistent mechanical stress. As the tissue attempts to heal, the normal regulatory mechanisms of cell growth can become disrupted, leading to disorganized growth patterns characteristic of dysplasia.

In contrast, while genetic predisposition, hormonal imbalance, and physiological changes associated with aging can impact cell function and contribute to various pathologies, they are not the primary drivers of the cellular changes seen in dysplasia. Instead, they may play a role in other types of pathological conditions, but chronic irritation and inflammation remain the hallmark precursors to dysplastic changes.