What kind of cell adhesion do integrins participate in?

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Prepare for the ASU HCR240 Human Pathophysiology exam. Study with interactive quizzes and multiple choice questions, each with hints and detailed explanations. Boost your pathophysiology knowledge for success on test day!

Integrins are a type of cell adhesion molecule that primarily mediate cell-matrix interactions. They are transmembrane proteins that connect the extracellular matrix (ECM) to the cytoskeleton of the cell, allowing cells to adhere to the surrounding matrix and respond to external signals. This interaction is crucial for various biological processes, including tissue development, wound healing, and the immune response.

The role of integrins in cell-matrix interactions involves binding to components of the ECM, such as fibronectin, collagen, and laminin. This binding not only provides structural support but also plays an essential role in signaling pathways that regulate cell behavior, such as migration, proliferation, and differentiation.

Other types of adhesion processes, such as homophilic adhesion, involve similar cells binding to each other rather than anchoring themselves to the extracellular matrix, which is not the primary function of integrins. Additionally, integrins are not limited to neural tissues; they are expressed widely across various cell types and tissues. Finally, fluid-based adhesion does not accurately describe the stable, permanent attachment functions of integrins, which rely on solid-phase interactions with the ECM.

Therefore, the key role of integrins in facilitating cell-matrix interactions reinforces the accuracy of the given

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