Which of the following are considered non-specific phagocytes?

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Prepare for the ASU HCR240 Human Pathophysiology exam. Study with interactive quizzes and multiple choice questions, each with hints and detailed explanations. Boost your pathophysiology knowledge for success on test day!

Non-specific phagocytes play a crucial role in the immune system, primarily through their ability to engulf and destroy pathogens as well as dead or dying cells. The correct answer identifies neutrophils, monocytes, and macrophages as non-specific phagocytes.

Neutrophils are often the first responders to sites of infection, rapidly migrating to areas of inflammation where they engulf bacteria and other foreign particles. Monocytes circulate in the bloodstream and can differentiate into macrophages when they migrate into tissues. Macrophages reside in tissues and are critical for both the initial inflammatory response and the resolution of inflammation. They are adept at recognizing and phagocytizing a wide variety of pathogens and debris without requiring specific antigens.

B cells and T cells are primarily involved in the adaptive immune response, recognizing specific antigens and generating targeted responses, which distinguishes them from the non-specific phagocytic action of the identified cells. Similarly, plasma cells, which are differentiated B cells that produce antibodies, and natural killer cells, which are part of the innate immune response but focus on targeting infected or transformed cells rather than phagocytosis, do not fit the criteria for non-specific phagocytes.

Thus, neutrophils, monocytes, and macrophages together

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